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Charles DUPRAS

Charles Dupras

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Professeur adjoint

École de santé publique - Département de médecine sociale et préventive

7101, av. du Parc office 3039

charles.dupras@umontreal.ca

Responsable de programme

École de santé publique - Département de médecine sociale et préventive

7101, av. du Parc office 3039

Travail 1 : 514 343-2498 #4881

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Expertises

Research projects Expand all Collapse all

Les comités d'éthique de la recherche (CER) en milieu collégial : mandat, gouvernance et ressources Projet de recherche au Canada / 2022 - 2024

Lead researcher : Emmanuelle Marceau
Co-researchers : Charles Dupras
Funding sources: FRQSC/Fonds de recherche du Québec - Société et culture (FQRSC)
Grant programs:

Publications Expand all Collapse all

Dupras, C.,* Knoppers, T., Palmour, N., Beauchamp, E., Liosi, S., Siebert, R., Berner, A.M., Beck, S., Charest I. and Y. Joly (2022) Researcher Perspectives on Ethics Considerations in Epigenetics: An International Survey. Clinical Epigenetics 14 (1): 1-13.

Dupras, C.*, and E. M. Bunnik (2022) Response to Open Peer Commentaries on Toward a Framework for Assessing Privacy Risks in Multi-Omic Research and Databases. American Journal of Bioethics: 1-3. https://doi.org/10.1080/15265161.2022.2105436

Saulnier, K*., A. Berner, S. Liosi, B. Earp, C. Berrios, S.O.M. Dyke, C. Dupras and Y. Joly. (2022) Studying Vulnerable Populations Through an Epigenetics Lens: Proceed with Caution. Canadian Journal of Bioethics 5 (1): 68-78. https://doi.org/10.7202/1087205ar

Knoppers T., E. Beauchamp, K. Dewar, S. Kimmins, G. Bourque, Y. Joly and C. Dupras*. (2021) The Omics of our Lives: Practices and Policies of Direct-to-Consumer Epigenetic and Microbiomic Testing Companies. New Genetics & Society 40 (4): 541-569. https://doi.org/10.1080/14636778.2021.1997576  

Dupras C.* and E. M. Bunnik (2021) Toward a Framework for Assessing Privacy Risks in Multi-omic Research and Databases. American Journal of Bioethics:1-32. https://doi.org/10.1080/15265161.2020.1863516 

Ravitsky V., S. Birko*, J. Le Clerc-Blain, H. Haidar, M-E. Lemoine, C. Dupras and A-M. Laberge (2020) Non-invasive Prenatal Testing: Views of Canadian Pregnant Women and Their Partners Regarding Pressures and Societal Concerns. AJOB Empirical Bioethics 12(1): 53-62. https://doi.org/10.1080/23294515.2020.1829173 

Joly Y.*, G. Dalpé, C. Dupras, B. Bévière Boyer, A. De Paor, E. Dove, P. Granados Moreno, C. Ho, C-H. Ho, K.O. Cathaoir, K. Kato, H. Kim, L. Song, T. Minssen, P. Nicolas, M. Otlowski, A.E.R.Prince, P.S. Athira, I. Van Hoyweghen, T.H. Voigt, C. Yamasaki and Y. Bombard (2020) Establishing the First International Genetic Discrimination Observatory. Nature Genetics 52(5): 466-468. https://doi.org/10.1038/s41588-020-0606-5 

Dupras C.*, S. Birko, A. Affdal, H. Haidar, M-E. Lemoine and V. Ravitsky (2020) Governing the Futures of Non-invasive Prenatal Testing: An Exploration of Social Acceptability Using the Delphi Method. Social Science & Medicine 304: 112930. https://doi.org/10.1016/j.socscimed.2020.112930 

Dupras C.*, J. Hagan and Y. Joly (2020) Overcoming Biases Together: Normative Stakes of Interdisciplinarity in Bioethics. AJOB Empirical Bioethics 11(1): 20-23. https://doi.org/10.1080/23294515.2019.1706209 

Dupras C.*, Y. Joly and E. Rial-Sebbag (2020) Human Rights in the Postgenomic Era: Challenges and Opportunities Arising with Epigenetics. Social Science Information 59(1): 12-34. https://doi.org/10.1177/0539018419900139 

Joly Y.*, C. Dupras, M. Pinkesz, S.A. Tovino and M.A. Rothstein (2020) Looking beyond GINA: Policy Approaches to Address Genetic Discrimination. Annual Review of Genomics and Human Genetics 21: 2.1-2.17. https://doi.org/10.1146/annurev-genom-111119-011436

Ben-Eghan C., R. Sun R., J. S. Hleap, A. Diaz-Papkovich, A.V. Grant, C. Dupras and S. Gravel* (2020) Don’t Ignore Genetic Data from Minority Populations. Nature 585: 184-186. https://doi.org/10.1038/d41586-020-02547-3 

Dupras C.*, E. Beauchamp and Y. Joly (2020) Selling Direct-to-consumer Epigenetic Testing: Are We Ready? Nature Reviews Genetics 22: 1-2. https://doi.org/10.1038/s41576-020-0215-2 

Smith E. and C. Dupras* (2020) Fair Subject Selection Procedures Must Consider Scientific Uncertainty and the Subjective Nature of Risk and Benefit Perception. American Journal of Bioethics 20(2): 33-35. http://dx.doi.org/10.1080/15265161.2019.1701744 

Joly Y.*, G. Marrocco and C. Dupras (2019) Risks of Compulsory Genetic Databases. Science 363(6430): 938-940. http://dx.doi.org/10.1126/science.aaw4347  

Saulnier K.M.*, D. Bujold, S.O.M. Dyke, C. Dupras, S. Beck, G. Bourque and Y. Joly (2019) Benefits and Barriers in the Design of Harmonized Access Agreements for International Data Sharing. Scientific Data 6(1): 1-6. https://doi.org/10.1038/s41597-019-0310-4 

Dupras C.*, S. Beck, M. A. Rothstein, A. Berner, K. M. Saulnier, M. Pinkesz, A. E. R. Prince, S. Liosi, L. Song and Y. Joly (2019) Potential (Mis)use of Epigenetic Age Estimators by Private Companies and Public Agencies: Human Rights Law Should Provide Ethical Guidance. Environmental Epigenetics 5(3): 1-12. https://doi.org/10.1093/eep/dvz018 

Dyke S.*, K. M. Saulnier, C. Dupras, D. Procaccini, A. Webster, K. Maschke, M. A. Rothstein, R. Siebert, J. Walter, S. Beck, T. Pastinen and Y. Joly (2019) Points-to-Consider on the Return of Results in Epigenetics Research. Genome Medicine 11(1): 31-40. https://doi.org/10.1186/s13073-019-0646-6 

Dupras C.*, K.M. Saulnier and Y. Joly (2019) Epigenetics, Ethics, Law and Society: A Multidisciplinary Review of Descriptive, Instrumental, Dialectical, Reflexive and Empirical Analyses. Social Studies of Science 49(5): 485-810. https://doi.org/10.1177/0306312719866007 

Laberge A-M.*, Birko S., Lemoine M-E., Le Clerc-Blain J., Haidar H., Affdal A.O., Dupras C., and V. Ravitsky (2019) Canadian Pregnant Women’s Preferences Regarding NIPT for Down Syndrome: The Information They Want, How They Want to Get it and With Whom They Want to Discuss it. Journal of Obstetrics and Gynaecology Canada. https://doi.org/10.1016/j.jogc.2018.11.003 

Birko S.*, V. Ravitsky, C. Dupras, A. Affdal, J. Le Clerc-Blain, H. Haidar, M.-E. Lemoine, A.-M. Laberge (2019) The Value of Non-Invasive Prenatal Testing: Preferences of Canadian Pregnant Women, their Partners, and Health Professionals Regarding NIPT Use and Access. BMC Pregnancy and Childbirth 19: 22. https://doi.org/10.1186/s12884-018-2153-y 

Dupras C.*, S. Birko, A. Affdal, H. Haidar, M-E. Lemoine and V. Ravitsky (2019) Benefits, Challenges and Ethical Principles Associated with Implementing Non-invasive Prenatal Testing: A Delphi Study. CMAJ Open 6(4): E513-E519. http://dx.doi/10.9778/cmajo.20180083 

Fortin A.* and C. Dupras (2018) L’humour macabre: un mécanisme de défense acceptable en soins critique? Revue canadienne de bioéthique 1(2): 69-75. https://cjb-rcb.ca/index.php/cjb-rcb/article/view/4 

Dupras C.*, L. Song, K. M. Saulnier and Y. Joly (2018) Epigenetic Discrimination: Emerging Applications of Epigenetics Pointing to the Limitations of Policies Against Genetic Discrimination. Frontiers in Genetics 8(202): 1-6. http://dx.doi/10.3389/fgene.2018.00202 

Williams-Jones B.*, R. Boulanger, V. Couture and C. Dupras (2017) Imagining Truly Open Access Bioethics: From Dreams to Reality. American Journal of Bioethics 17(10): 19-20. http://dx.doi.org/10.1080/15265161.2017.1365193 

Dupras C.*, B. Williams-Jones and V. Ravitsky (2017) Biopolitical Barriers to a Potterian Bioethics: The (Potentially) Missed Opportunity of Epigenetics. American Journal of Bioethics 17(9): 15-7. http://dx.doi.org/10.1080/15265161.2017.1353173 

Saulnier K. M.* and C. Dupras (2017) Race in the Post-Genomic Era: Social Epigenetics Calling for Interdisciplinary Ethical Safeguards.American Journal of Bioethics 17(9): 58-60. http://dx.doi.org/10.1080/15265161.2017.1353182 

Dupras C.* (2017) Rapprochement des pôles nature-culture par l’épigénétique : portrait d’un bouleversement épistémologique attendu. Ateliers de l'éthique/Ethics Forum 12(2-3), 120–145. http://dx.doi/10.7202/1051278ar 

Roy M-C.*, C. Dupras and V. Ravitsky (2017) The Epigenetic Effects of Assisted Reproductive Technologies: Ethical Considerations. Journal of Developmental Origins of Health and Disease 8(4): 436-42. http://dx.doi.org/10.1017/S2040174417000344 

Murdoch B.*, V. Ravitsky, U. Ogbogu, S. Ali-Khan, G. Bertier, S. Birko, T. Bubela, J. DeBeer, C. Dupras, M. Ellis, P. Granados Moreno, Y. Joly, K. Kamenova, A. Marcon, Z. Master, M. Paulden, F. Rousseau, T. Caulfield (2017) Non-Invasive Prenatal Testing and the Unveiling of an Impaired Translation Process. Journal of Obstetrics and Gynaecology Canada 39(1): 10-17. http://dx.doi.org/10.1016/j.jogc.2016.09.004 

Dupras C.* and V. Ravitsky (2016) The Ambiguous Nature of Epigenetic Responsibility. Journal of Medical Ethics 42(8): 534-41. http://dx.doi.org/10.1136/medethics-2015-103295 

Dupras C.* and V. Ravitsky (2016) Epigenetics in the Neoliberal ‘Regime of Truth’: A Biopolitical Perspective on Knowledge Translation. Hastings Center Report 46: 1-10. http://dx.doi.org/10.1002/hast.522 

Haidar H.*, C. Dupras and V. Ravitsky (2016) A Review of the Ethical, Legal and Social Implications of Non-Invasive Prenatal Testing. BioéthiqueOnline 5/6: 1-14. http://www.bioethiqueonline.ca/5/6 

Dupras C.*, V. Ravitsky and B. Williams-Jones (2014) Epigenetics and the Environment in Bioethics. Bioethics 28: 327–334. http://dx.doi.org/10.1111/j.1467-8519.2012.02007.x 

Dupras C.*, G. Andelfinger, M. Paré, M. Thibeault, and B. Godard (2014) Influence of Demographic Characteristics of Participants on Consent to Genomic Research into Congenital Heart Disease. Journal of Clinical Research and Bioethics 5 (5): 1-5. http://dx.doi.org/10.4172/2155-9627.1000199 

Dupras C.* and V. Ravitsky (2013) Disclosing Genetic Information to Family Members: The Role of Empirical Ethics. Encyclopedia of Life Sciences (eLS): 1-6. http://dx.doi.org/10.1002/9780470015902.a0005959.pub2 

Dupras C.* and B. Williams-Jones (2012) The Expert and the Lay Public: Reflections on H1N1 and the Risk Society. American Journal of Public Health 102(4): 591-5. http://dx.doi.org/10.2105/AJPH.2011.300417 

Dupras C.* and B. Williams-Jones (2012) Dupras and Williams-Jones Respond. American Journal of Public Health 102(7): e12-e13. http://dx.doi.org/10.2105/AJPH.2012.300788

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